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Best Urology & Andrology Clinic in Delhi/NCR - Uroclinic

Uroclinic : East Patel Nagar

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Address : UROCLINIC 25/34, Ground Floor, Govind Lal Sikka Marg, Near Rajendra Place Metro Station (Pillar No. 161), East Patel Nagar New Delhi 110008

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Urology Disease

Vesico Ureteric Reflux

Vesicoureteral reflux (VUR) is a condition characterized by the abnormal flow of urine from the bladder back into the ureters and sometimes the kidneys. This retrograde flow of urine can lead to urinary tract infections (UTIs), kidney damage, and other complications. Understanding the causes, symptoms, diagnosis, and treatment options for vesicoureteral reflux is crucial for effective management and prevention of complications.

Understanding Vesicoureteral Reflux (VUR):

Vesicoureteral reflux (VUR) is a condition in which urine flows backward from the bladder into one or both ureters and potentially into the kidneys. This abnormal flow of urine can occur during bladder filling or emptying, leading to a higher risk of urinary tract infections and potential kidney damage.

Causes and Risk Factors:

Vesicoureteral reflux can be congenital (present at birth) or acquired, and may be associated with various factors, including:

  • Congenital Defects: Anomalies in the development of the ureterovesical junction (where the ureter connects to the bladder) can result in incompetent valves, allowing urine to reflux into the ureters.
  • Incomplete Bladder Emptying: Conditions that prevent the complete emptying of the bladder, such as neurogenic bladder or bladder outlet obstruction, can increase the risk of vesicoureteral reflux.
  • Genetic Factors: Family history of vesicoureteral reflux or other urinary tract abnormalities may predispose individuals to develop the condition.
  • Urinary Tract Infections: Recurrent UTIs can lead to inflammation and scarring of the ureterovesical junction, increasing the risk of vesicoureteral reflux.
  • Bladder Dysfunction: Conditions that affect bladder function, such as detrusor sphincter dyssynergia or overactive bladder, can contribute to vesicoureteral reflux by increasing intravesical pressure during bladder filling.

Common Symptoms:

The symptoms of vesicoureteral reflux may vary depending on the severity of the condition and whether it is associated with other urinary tract abnormalities. Common symptoms may include:

  • Recurrent Urinary Tract Infections: Children with vesicoureteral reflux may experience frequent UTIs, which may be accompanied by symptoms such as fever, dysuria (painful urination), urgency, and frequency.
  • Voiding Dysfunction: Some children with vesicoureteral reflux may experience voiding dysfunction, such as urinary urgency, urinary frequency, or daytime wetting (enuresis).
  • Abdominal or Flank Pain: In cases of severe vesicoureteral reflux or associated kidney abnormalities, children may experience abdominal or flank pain, particularly during UTI episodes or periods of increased urinary reflux.

Diagnosis and Evaluation:

1. Medical History and Physical Examination: A healthcare provider, such as a urologist, will begin by obtaining a detailed medical history and performing a physical examination. The urologist may ask about symptoms, urinary tract infections, voiding patterns, and family history of urinary tract abnormalities.

2. Imaging Studies: Imaging studies are essential for diagnosing vesicoureteral reflux and assessing its severity and potential complications. These may include:

  • Voiding Cystourethrogram (VCUG): A contrast dye is injected into the bladder through a catheter, and X-ray images are taken while the patient urinates to visualize any reflux of contrast into the ureters or kidneys.
  • Renal Ultrasound: An ultrasound scan of the kidneys and urinary tract may be performed to evaluate kidney size, shape, and position and identify any structural abnormalities or signs of hydronephrosis (dilation of the kidneys).
  • Nuclear Medicine Scans: Radionuclide imaging studies such as a technetium-99m dimercaptosuccinic acid (DMSA) scan or a technetium-99m mercaptoacetyltriglycine (MAG3) scan may be used to assess kidney function, renal scarring, and drainage patterns in cases of suspected vesicoureteral reflux.

3. Grading System: Vesicoureteral reflux is often graded based on its severity, ranging from grade I (mildest) to grade V (most severe), using the International Reflux Study in Children (IRC) grading system. This grading system helps guide treatment decisions and predicts the risk of complications associated with vesicoureteral reflux.

Treatment and Management:

1. Observation: In cases of mild vesicoureteral reflux (grades I and II) without associated complications or recurrent UTIs, close observation with regular follow-up visits may be recommended to monitor the condition and assess for resolution over time.

2. Antibiotic Prophylaxis: Antibiotic prophylaxis may be prescribed to children with vesicoureteral reflux to prevent recurrent urinary tract infections and minimize the risk of kidney damage. Antibiotics are typically given in low doses on a daily basis or after specific events (e.g., during voiding cystourethrogram, UTI).

3. Surgical Intervention: Surgical intervention may be necessary to correct vesicoureteral reflux and prevent complications such as kidney damage or recurrent UTIs. Surgical options may include:

  • Endoscopic Injection: Minimally invasive procedure where a bulking agent (e.g., dextranomer/hyaluronic acid copolymer) is injected into the submucosal layer of the ureterovesical junction to create a valve-like mechanism and prevent urinary reflux.
  • Open/lap/robotic Surgery: Surgical procedures such as ureteral reimplantation or ureteral advancement may be performed to surgically correct vesicoureteral reflux, particularly in cases of high-grade reflux or failed endoscopic therapy.

4. Follow-Up Care: Regular follow-up visits with a urologist , including monitoring of kidney function, imaging studies, and urine cultures, are essential for children with vesicoureteral reflux to assess treatment response, monitor for complications, and ensure optimal kidney health.

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UROCLINIC 25/34, Ground Floor, Govind Lal Sikka Marg, Near Rajendra Place Metro Station (Pillar No. 161), East Patel Nagar New Delhi 110008

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